A young girl whose cancer diagnosis sparked a global hunt for “some of the rarest blood in the world” is in remission.

Zainab Mughal, from Florida, was diagnosed with neuroblastoma, an aggressive form of cancer, when she was two, and as part of her treatment needed a series of blood transfusions.

But the search for donors proved far more difficult than usual because she is missing an antigen, called Indian B, which most people have in their red blood cells.

Any blood containing the antigen would be rejected by her body.

It meant the hunt had to be confined to a very specific population, people whose two birth parents are both 100% of Pakistani, Indian or Iranian origin.

Even within that population, only 4% of people have the unusual genetic variation, according to OneBlood, the Florida-based charity that is leading the search.

On top of that, donors needed to have type O or A blood.

It was described by OneBlood as “some of the rarest blood in the world” and, while three compatible donors were quickly found, more were needed because of the number of transfusions Zainab required in the course of her treatment.

OneBlood posted about Zainab’s story on Facebook, requesting for donors to come forward, in December 2018, and in the following days, more than 25,000 people came forward, leading to over 4,000 units of blood being tested.

Zainab Mughal celebrates her birthday
Zainab Mughal is in remission after a global search for blood donors (OneBlood)

Ultimately the search unearthed another two matches, completing a pool of five donors, two from the United States, two from the UK and one from Australia.

Each of the five donated repeatedly over the course of Zainab’s treatment, with the blood shipped to OneBlood so it was available for Zainab when needed.

A statement from OneBlood read: “These five donors played a significant role in saving Zainab’s life.

“Over the course of her treatment, Zainab received more than a dozen blood and platelet transfusions.

“Doctors say it would not have been possible for her to have endured the chemotherapy, surgery and two bone marrow transplants without the blood.”

Zainab, who recently celebrated her fourth birthday, is now in remission and her parents are optimistic for the future.

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Help save Zainab! Visit the link in our bio for information. . Zainab is a two year old in South Florida with an aggressive form of cancer called neuroblastoma. . Her blood is extremely rare because she is missing a common antigen that most people carry on their red blood cells. The antigen is called “Indian B.” For a person to be a possible match for Zainab, they must also be missing the Indian B antigen, or the little girl’s body will reject the blood. . To be a match, a donor must meet the following criteria: . 1. Exclusively Pakistani, Indian or Iranian decent – meaning both parents are 100% Pakistani, Indian or Iranian. . 2. Must be blood type O or A . 3. Coordinate with OneBlood in advance to ensure the additional compatibility testing is performed. . If you meet this criteria please donate at your earliest convenience! . . . . . . #rareblood #blooddonor #blooddonation #blooddonor #blooddonors #donateblood #donatebloodsavelives #blooddonate #donatebloodsavelife #bloodtransfusion #bloodtransfusions #blooddonorsneeded #blooddonorssavelives #donatebloodtoday #donatebloodsavealife #donatebloodandsavelives #donatebloodnow #doubleredcells #wholeblood #wholeblooddonation #blooddrive #apositive #anegative #anegativebloodtype #shareyourpower #neuroblastoma #childhoodcancerawareness #neuroblastomaawareness #neuroblastomawarrior #opositive

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Zainab’s father Raheel Mughal said: “For those five donors, they are surely a life saver for us.

“They have given our daughter a new life and we are very thankful to them.”

He added: “Our best hope is that the cancer never relapses and we’re very optimistic that it will not come back.

“We’re very much looking forward to having a very normal life.”

One donor from the UK was a British Indian mother of two from Nottingham who said she felt “privileged” to help another human being with her blood donation.

The 50-year-old, who chose to remain anonymous, said: “I didn’t know who the recipient was when I donated but I do know now… I am very humbled that I have played a small part in aiding someone’s recovery from illness.

“I do hope the publicity encourages more people to donate, especially from the Asian community, as even a single donation can make a massive difference to someone who needs it.”

OneBlood said Zainab’s case highlights the need for a diverse blood supply.

Spokeswoman Susan Forbes said: “There are many other patients, just like Zainab who have extraordinarily rare blood needs.

“Finding compatible blood for these patients comes down to genetics.

“The only way to find specially matched blood for these patients is to increase the diversity of the donor population.”